Organic Chemistry 354 Quiz - December 4, 1997

Dr. Sundin

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A nonapeptide gave the following amino acids on complete hdrolysis:

Ala = 2; Gly = 2; Phe = 1; Pro = 2; and Ser = 2.

Edman degradation gave Gly while carboxypeptidase A gave Ser. Partial hydrolysis gave a complex mixture from which only five tripeptides (see below) were isolated. Give the structure of the nonapeptide.

tripeptides:

Ala-Ala-Pro
Gly-Ser-Pro
Pro-Ala-Ala
Pro-Phe-Ser
Ser-Pro-Ala

Answer

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